Research Topic

Some chaperone-mediated events in stressed and non-stressed cells 

 

Our group is interested in the proteins of the molecular stress response, the molecular chaperones. These proteins are characterised by their stress-protective function. They also have functions under normal growth conditions. Using the model organism Caenorhabditis elegans we investigate the participation of Hsp90 and its cofactors during development and attempt to uncover the biochemical mechanisms.

 

Research projects

Mechanism of the Hsp90 system in Caenorhabditis elegans

Mechanism of the C. elegans Hsc70 Systems

Heat shock response and protein aggregation

Chemical modulation of the chaperone system

Analytical ultracentrifugation